The effect for a casual observer is breathtaking: the building is a bizarre and visually satisfying amalgam (perhaps mishmash is a better term) of colors and textures, weirdly canted angles and shapes that appear jammed together at random.
The building was designed by Frank Gehry, who also designed other wacky architectural masterpieces-slash-modernist-nightmares, including Disney Hall in Los Angeles, and the Experience Music Project in Seattle.
Floor-to-ceiling glass walls in some offices means that privacy is impossible. The otherworldly angles, while striking, make hanging bookshelves well-nigh impossible.
The Wikipedia article on the Stata Center lists other defects, including a lack of soundproofing, a tendency to induce vertigo in its inhabitants, and a giant-sized price tag.
Oh, and it's probably not a good sign that MIT is suing Gehry, for massive design flaws leading to cracked masonry, flooding, and mold.